ENC NMN 12000
Reverse Aging, Youthful Elixir
【Composition】: Each capsule contains 150mg NMN, 10mg Resveratrol, 5mg Astaxanthin, unique formula (truffle, spirulina, Y-amino acid, tomato yeast powder, phosphatidylserine, broccoli, grape cluster kale, avocado, double embrace mushroom, blueberry).
【Suitable for】: People who want to maintain youthfulness and below:
- Middle-aged and elderly people, for assisting in improving various sub-health and aging-related diseases;
- Adults with high stress, severe physical exhaustion, frequent late nights, and easy fatigue;
- Individuals with poor mental state, neurosensitivity, depression, poor memory, insomnia, etc.;
Individuals with poor skin quality, can be used to improve skin quality and delay skin aging.
High-dose NMN combined with Resveratrol and Astaxanthin for comprehensive maintenance of human health, improving sub-health, preventing diseases, energizing the body, anti-aging, and maintaining youthfulness.
★ Understanding NMN: With the development of life sciences, humans have finally recognized that the fundamental cause of aging lies in the accumulation of damage to the genetic carrier-DNA and the energy factory-mitochondria within cells as age increases. The self-repair ability of cells gradually decreases with age. At the same time, external factors such as environmental pollution, drugs, radiation, etc., accelerate genetic damage and aging. As early as 1904, it was discovered by British biologists that by 2014, David Sinclair’s laboratory at Harvard University confirmed that NMN is a crucial precursor of the coenzyme NAD+ in the body. NAD+ is not only an important raw material for the DNA repair system inside cells but also a key link between the cell nucleus and the mitochondria responsible for energy synthesis. Furthermore, the level of NAD+ in the body is closely related to the activity of the sirtuins protein family, which is associated with prolonging lifespan and inhibiting aging. However, NAD+ cannot be absorbed directly by cells. Therefore, scientists have found a precursor of NAD+ that can be absorbed and utilized by cells – NMN. Orally administered NMN rapidly reaches the bloodstream within 10 minutes and gradually increases the level of NAD+ in the body within 30 minutes! NMN can effectively compensate for the decrease in NAD+ content in the body due to aging, significantly inhibit the metabolic decline, weight gain, and osteoporosis caused by aging. In addition, NMN has been found to effectively prevent age-related retinal degeneration and improve neural function. These findings have made NMN a focus of research in the field of aging medicine, with nearly a hundred papers published in authoritative academic journals such as “Cell,” “Nature,” and “Science” in just a few years, detailing its efficacy and mechanisms of action. For example, the latest research report published in “Cell” in March 2018 showed that NMN successfully reversed vascular death and muscle atrophy in aging animals, greatly enhancing their endurance. The physical strength and explosiveness of aging animals taking NMN exceeded that of same-aged animals not taking it by more than 60%, even surpassing the level of young animals. Most surprisingly, the increase in NAD+ brought about by oral NMN can extend the lifespan of experimental animals similar to humans by more than 30%. Between 2016 and 2018, research institutions such as Harvard University, Washington University, and Osaka University in Japan conducted detailed evaluations of the anti-aging effects of NMN from various angles, such as reversing muscle atrophy, improving physical fitness, inhibiting age-related cognitive decline, reversing vascular death, and protecting cardiovascular and cerebrovascular function. The results consistently indicate that NMN has a significant and comprehensive effect on inhibiting aging.
- What is NMN? NMN is a precursor of NAD+, and its function is reflected through NAD+. NAD+, also known as coenzyme I, is involved in thousands of reactions in every cell but cannot be directly absorbed by cells. Therefore, scientists have found a precursor of NAD+ that can be absorbed and utilized by cells – NMN. NMN is an inherent substance in the human body and is also abundant in some fruits and vegetables. In the human body, NAD+ is an essential coenzyme component for hundreds of enzymes, including the longevity enzyme proteins. It plays a leading role in hundreds of life activities in the human body. After entering the body, NMN becomes NAD+ and plays an important role in energy and substance metabolism. Regarding the tricarboxylic acid cycle alone, the tricarboxylic acid cycle is the final metabolic pathway of the three major nutrients (carbohydrates, lipids, amino acids) in the human body and is also the hub of the metabolism of carbohydrates, lipids, and amino acids. The tricarboxylic acid cycle also provides a large amount of energy for the organism and is the hub of organism energy. NAD+ has a fundamental impact on human health. However, with age, the content of NAD+ in the human body gradually decreases, communication between mitochondria and the cell nucleus is impaired, and the decrease in NAD+ also impairs the cell’s ability to produce energy, leading to aging and disease.
- What are the main functions of NMN?
- Catalyzes the production of more than 95% of the energy needed for life activities. Mitochondria in human cells are the power plants of cells, and coenzyme I is an important coenzyme in the tricarboxylic acid cycle of aerobic oxidative metabolism in mitochondria, which generates energy molecules ATP. As a hydrogen ion acceptor, it transfers hydrogen ions to oxygen, allowing the three major nutrients that the human body obtains, carbohydrates, fats, and proteins, to be converted into the energy and other substances needed for life activities through the tricarboxylic acid cycle.
- Repairs genetic genes (DNA). Coenzyme I (NAD+) is consumed as a substrate to generate gene repair enzyme PARP1, and it can also separate the inactive PARP1 bound by protein DBC1 to restore activity. PARP1 can recode damaged genes according to the normal gene sequence, thereby repairing genes.
- Anti-aging. Coenzyme I (NAD+) maintains chemical communication between the cell nucleus and mitochondria. If this communication is weakened, mitochondrial degeneration will occur, which is an important cause of cell aging. In addition, coenzyme I is the only substrate that is consumed and generates histone deacetylase Sirtuins, which is known as the longevity protein. It can eliminate the continuous increase in epigenetic noise in the process of cell metabolism, maintain normal gene expression, maintain the specialized functions of cells, and slow down the process of cells evolving into aging cells.
- Maintaining the regenerative ability of capillaries. When muscle cells move, they release growth factors, and capillary endothelial cells receive growth factors to accelerate growth. This process depends on the long-life protein Sirtuin1 generated by coenzyme I, the older the person, the less coenzyme I, the worse the effect of exercise on muscle growth. Effect 5: Alcohol Metabolism Alcohol metabolism is divided into two